Neurological manifestations are a significant complication of coronavirus disease (COVID-19), but underlying mechanisms aren’t well understood. The development of animal models that recapitulate the neuropathological findings of autopsied brain tissue from patients who died from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are critical for elucidating the neuropathogenesis of infection and disease. Here, we show neuroinflammation, microhemorrhages, brain hypoxia, and neuropathology that is consistent with hypoxic-ischemic injury in SARS-CoV-2 infected non-human primates (NHPs), including evidence of neuron degeneration and apoptosis. Importantly, this is seen among infected animals that do not develop severe respiratory disease, which may provide insight into neurological symptoms associated with “long COVID”. Sparse virus is detected in brain endothelial cells but does not associate with the severity of central nervous system (CNS) injury. We anticipate our findings will advance our current understanding of the neuropathogenesis of SARS-CoV-2 infection and demonstrate SARS-CoV-2 infected NHPs are a highly relevant animal model for investigating COVID-19 neuropathogenesis among human subjects. COVID-19 can result in neurological manifestations and animal models could provide insights into the mechanisms. Here, the authors describe neuroinflammation, microhemorrhages and brain hypoxia in SARS-CoV-2 infected non-human primates, including in animals that don’t develop severe respiratory disease.
— Read on www.nature.com/articles/s41467-022-29440-z
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Politician watch: Wes Streeting
For the first time, a new study has investigated the effects of mild COVID (that is, infection that doesn’t lead to a hospital admission) on the brain. The findings may further explain some of the brain changes contributing to long COVID. …
— Read on www.psypost.org/2022/03/even-mild-cases-of-covid-19-might-result-in-brain-shrinkage-and-impaired-cognitive-function-62755
Court ‘will remain concerned to ensure that these proceedings are not used as a vehicle to air broader issues’.
— Read on www.lawgazette.co.uk/law/judge-lambasts-parties-animosity-in-latest-dr-bitcoin-ruling/5112001.article
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Asbestos: talc; Johnson & Johnson
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Ukraine 🇺🇦: John Mearsheimer 2015
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Palestine 🇵🇸 Ireland 🇮🇪
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P&O solidarity from Dutch dockers
Question – I have received a parking charge notice from euro car parks – D4. Find the answer to this and other Traffic Law questions on JustAnswer
— Read on www.justanswer.co.uk/traffic-law/7z73k-received-parking-charge-notice-euro-car-parks.html
The Good Law Project, R (On the Application Of) v The Secretary of State for Health And Social Care [2022] EWCA Civ 355 (24 March 2022)
— Read on www.bailii.org/ew/cases/EWCA/Civ/2022/355.html
A review of the claims that can be brought under the Law Reform (Miscellaneous Provisions) Act 1934 and the Fatal Accidents Act 1976 and the principles governing such claims.
— Read on www.ropewalk.co.uk/knowledge-sharing/blog/personal-injury/1753/fatal-accident-claims-a-brief-overview
Review
Why is COVID-19 less severe in children? A review of the proposed mechanisms underlying the age-related difference in severity of SARS-CoV-2 infections
— Read on adc.bmj.com/content/106/5/429
@EnemyInAState: 1/ Covid, England, BA2: Outbreak of BA2 at a University HallsHealthy 18-19 years olds who’ve had Covid multiple times before taken ‘aback about how bad they feel’—students ‘encouraged’ to go to lectu……
— Read on threadreaderapp.com/thread/1505299917035782155.html
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Yemen 🇾🇪: UK’s involvement
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Police watch: Spain
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Coronavirus: strokes
There is no going back to a pre-pandemic normal – only forward to a new one.
— Read on theconversation.com/eight-changes-the-world-needs-to-make-to-live-with-covid-177678
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Police watch: Met Police
Trade union firm Thompsons says P&O’s mass sacking of ship crews is ‘unlawful’.
— Read on www.lawgazette.co.uk/news/pando-faces-legal-action-over-shocking-disregard-for-employment-law/5111915.article
PFIZER have included the common gastrointestinal symptoms, fatigue and brain fog as potential adverse events of the jab. New documents have been released after a federal judge ordered the data to be made public.
— Read on www.express.co.uk/life-style/health/1577745/Pfizer-vaccine-side-effects-adverse-effects
Majority verdict in favour of Bott & Co in its client capture dispute with Ryanair.
— Read on www.lawgazette.co.uk/news/supreme-court-backs-solicitors-over-right-to-recover-costs/5111872.article
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Stress at work: Weightmans 2017
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Police watch: Russia
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Coronavirus: increase in cases
I’ve been locked out of my Twitter account over this post.
— Read on asawinstanley.substack.com/p/twitter-is-censoring-reporting-on
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NATO control of the media
UKRAINE NEO-NAZIS PICTURED WITH UK-MADE ROCKET LAUNCHERS
— Read on declassifieduk.org/ukraine-neo-nazis-pictured-with-uk-made-rocket-launchers/
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Ukraine 🇺🇦: neo-Nazis
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Money laundering: Londongrad
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FTP: blockheed; block Lockheed
SARS-CoV-2 is associated with changes in brain structure in UK Biobank
— Read on www.nature.com/articles/s41586-022-04569-5
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Russia 🇷🇺; Boris Johnson – Lebedev
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Coronavirus: BA2 – Hong Kong
Law Society Gazette
— Read on edition.pagesuite-professional.co.uk/html5/reader/production/default.aspx
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Protected: Experts: NIHL military
TechStartups – Coverage of Technology News, technology startups, Emerging technology, venture capital funding, and Silicon Valley
— Read on techstartups.com/2022/02/26/new-swedish-study-shows-pfizer-vaccine-becomes-dna-liver-cells-fast-6-hours-vitro/
Ukraine’s National Guard praised neo-Nazi fighters from white-supremacist Azov movement for greasing bullets with pig fat to kill Russian Muslims, demonizing them as “orcs”
— Read on multipolarista.com/2022/02/27/ukraine-national-guard-nazi-muslim-orcs-lard/
https://twitter.com/rango1917/status/1498439693985370116?s=21
Geographical clustering of the earliest known COVID-19 cases and the proximity of positive environmental samples to live-animal vendors suggest that the Huanan Seafood Wholesale Market in Wuhan was the site of origin of the COVID-19 pandemic.
— Read on zenodo.org/record/6299600
have
Belsner v CAM Legal Services
— Read on www.lawgazette.co.uk/news/vos-halts-pi-fees-appeal-after-wider-issues-raised/5111609.article
Donetsk and Luhansk people’s republics
— Read on www.ft.com/content/b4bf6296-eb4d-4a26-9d46-e252b92b9837
A detailed study by Max Planck Institute shows the maximum risks of being infected by SARS-CoV-2 for different scenarios with and without masks – REGENHEALTHSOLUTIONS (RHS)
— Read on www.regenhealthsolutions.info/2021/12/04/a-detailed-study-by-max-planck-institute-shows-the-maximum-risks-of-being-infected-by-sars-cov-2-for-different-scenarios-with-and-without-masks/
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Politician watch: The Israel Lobby
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Police watch: Germany
President Eisenhower warns of military-industrial complex
— Read on www.history.com/
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Police watch: Canada
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Police watch: Canada
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Police watch: Canada
UK has begun using drugs for covid-19 cases before they become severe
— Read on www.newscientist.com/article/2302731-uk-has-begun-using-drugs-for-covid-19-cases-before-they-become-severe/
Galloway: the despicable record of a Red-Brown poseur
— Read on shirazsocialism.wordpress.com/2021/06/06/galloway-the-despicable-record-of-a-red-brown-poseur/
Marxist website defending the ideas of Marxism as a tool for workers and youth today – by the International Marxist Tendency.
— Read on www.marxist.com/the-awakening-of-the-turkish-working-class.htm
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Coronavirus: 7BR and Weightmans
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Coronavirus: Peoples Covid Inquiry
We’re holding our People’s Covid Inquiry now because we don’t think it’s too soon to start learning lessons about this crisis.
People are still dying from COVID-19. We believe 100,000 deaths were avoidable. We all deserve to know how and why this happened.
Learn lessons, save lives.
— Read on www.peoplescovidinquiry.com/
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D-Notices
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Starmer – Coventry bin men dispute
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Protected: SSD
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Coronavirus: vulnerable people
Prince Andrew? Or Virginia Giuffre?
— Read on rozenberg.substack.com/p/who-won
New research points to possible reason for long COVID
— Read on m.jpost.com/health-and-wellness/article-696452
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Cancer claims for fire fighters
BREAKING: High Court rules Dido Harding and Mike Coupe appointments were unlawful – Good Law Project
— Read on goodlawproject.org/update/dido-harding-mike-coupe-unlawful/
Information about the Courts and Tribunals Judiciary of England and Wales. Read the latest judgments, news and speeches.
— Read on www.judiciary.uk/judgments/the-queen-on-the-application-of-1-good-law-project-2-runnymede-trust-v-1-prime-minister-sshsc/
In its weekly update the UKHSA revealed the strain had been detected in the UK and was ‘currently under monitoring’. It evolved in someone that caught Delta and Omicron at the same time.
— Read on www.dailymail.co.uk/news/article-10502843/Health-chiefs-officially-keeping-tabs-variant-thats-Omicron-Delta-merger.html
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