Acute and postacute sequelae associated with SARS-CoV-2 reinfection
— Read on www.nature.com/articles/s41591-022-02051-3

Acute and postacute sequelae associated with SARS-CoV-2 reinfection
— Read on www.nature.com/articles/s41591-022-02051-3

Fact Check-UK Government tender notice for operational ration packs is a ‘regular contract’ for the Armed Forces
— Read on www.reuters.com/article/factcheck-mod-rations-idUSL1N3070KB
LEAKED GRANT PROPOSAL DETAILS HIGH-RISK CORONAVIRUS RESEARCH
— Read on theintercept.com/2021/09/23/coronavirus-research-grant-darpa/
Doctors ‘ashamed’ by chaotic scenes in new Royal Liverpool Hospital
— Read on www.liverpoolecho.co.uk/news/liverpool-news/doctors-ashamed-chaotic-scenes-new-25915017
Stanford Medicine scientists pinpoint COVID-19 virus’s entry and exit ports inside our noses
— Read on med.stanford.edu/news/all-news/2023/01/covid-virus-infection-nasal.html
Background: Although most children may experience mild to moderate symptoms and do not require hospitalization, there are little data on cardiac involvement in COVID-19. However, cardiac involvement is accurately demonstrated in children with MISC. The objective of this study was to evaluate cardiac mechanics in previously healthy children who recovered from severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in a long-term follow-up by means of two-dimensional speckle-tracking echocardiography (STE). Methods: We analyzed a cohort of 157 paediatric patients, mean age 7.7 ± 4.5 years (age range 0.3–18 years), who had a laboratory-confirmed diagnosis of SARS-CoV-2 infection and were asymptomatic or mildly symptomatic for COVID-19. Patients underwent a standard transthoracic echocardiogram and STE at an average time of 148 ± 68 days after diagnosis and were divided in three follow-up groups (<180 days, 180–240 days, >240 days). Patients were compared with 107 (41 females—38%) age- and BSA-comparable healthy controls (CTRL). Results: Left ventricular (LV) global longitudinal strain (post-COVID-19: −20.5 ± 2.9%; CTRL: −21.8 ± 1.7%; p < 0.001) was significantly reduced in cases compared with CTRLs. No significant differences were seen among the three follow-up groups (p = NS). Moreover, regional longitudinal strain was significantly reduced in LV apical-wall segments of children with disease onset during the second wave of the COVID-19 pandemic compared to the first wave (second wave: −20.2 ± 2.6%; first wave: −21.2 ± 3.4%; p = 0.048). Finally, peak left atrial systolic strain was within the normal range in the post-COVID-19 group with no significant differences compared to CTRLs. Conclusions: Our study demonstrated for the first time the persistence of LV myocardial deformation abnormalities in previously healthy children with an asymptomatic or mildly symptomatic (WHO stages 0 or 1) COVID-19 course after an average follow-up of 148 ± 68 days. A more significant involvement was found in children affected during the second wave. These findings imply that subclinical LV dysfunction may also be a typical characteristic of COVID-19 infection in children and are concerning given the predictive value of LV longitudinal strain in the general population.
— Read on www.mdpi.com/2077-0383/12/1/186
In the most comprehensive autopsy tissue study conducted to date, researchers have found traces of SARS-CoV-2 throughout the entire body, from the brain to the heart. The findings support research into antiviral drugs as possible treatment for long COVID.
— Read on newatlas.com/science/covid-autopsy-study-virus-brain-body/
Face masks or respirators (N95/KN95s) effectively filter virus-sized particles in laboratory settings
— Read on www.cdc.gov/mmwr/volumes/71/wr/mm7106e1.htm
Coronavirus infections, like those caused by the Severe Acute Respiratory Syndrome coronavirus (SARS-CoV-1 and SARS-CoV-2) and the Middle East respiratory syndrome coronavirus (MERS), can cause death in humans through significant tissue damage in major…
— Read on www.sciencealert.com/coronavirus-death
Twice-daily nasal irrigation reduces COVID-related illness, death
— Read on jagwire.augusta.edu/twice-daily-nasal-irrigation-reduces-covid-related-illness-death/
COVID-19: Things everyone should know (Part 1: Immune System)
— Read on pingthread.com/thread/1573772566346567680
Is immunity debt or immunity theft to blame for children’s respiratory virus spike?
— Read on www.tpr.org/bioscience-medicine/2022-12-27/is-immunity-debt-or-immunity-theft-to-blame-for-childrens-respiratory-virus-spike
Rapid initiation of nasal saline irrigation to reduce severity in high-risk COVID+ outpatients
— Read on pubmed.ncbi.nlm.nih.gov/36007135/
What this means for neurologic COVID symptoms remains elusive
— Read on www.medpagetoday.com/neurology/longcovid/102384
COVID-19 vaccine boosters for young adults: a risk benefit assessment and ethical analysis of mandate policies at universities
— Read on jme.bmj.com/content/early/2022/12/05/jme-2022-108449

bioRxiv – the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
— Read on www.biorxiv.org/content/10.1101/2022.12.22.521696v1
UK Government will stop publishing Covid data from January as country moves into phase of ‘living with the virus’
— Read on www.dailymail.co.uk/news/article-11573653/UK-Government-stop-publishing-Covid-data-January-country-living-virus.html