Author: Pete's Library
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Politician watch: Shabina Mahmood
The COVID-19 pandemic has resulted in upwards of 6.8 million deaths over the past three years, and the frequent emergence of variants continues to strain global health. Although vaccines have greatly helped mitigate disease severity, SARS-CoV-2 is likely to remain endemic, making it critical to understand its viral mechanisms contributing to pathogenesis and discover new antiviral therapeutics. To efficiently infect, this virus uses a diverse set of strategies to evade host immunity, accounting for its high pathogenicity and rapid spread throughout the COVID-19 pandemic. Behind some of these critical host evasion strategies is the accessory protein Open Reading Frame 8 (ORF8), which has gained recognition in SARS-CoV-2 pathogenesis due to its hypervariability, secretory property, and unique structure. This review discusses the current knowledge on SARS-CoV-2 ORF8 and proposes actualized functional models describing its pivotal roles in both viral replication and immune evasion. A better understanding of ORF8’s interactions with host and viral factors is expected to reveal essential pathogenic strategies utilized by SARS-CoV-2 and inspire the development of novel therapeutics to improve COVID-19 disease outcomes.
— Read on www.mdpi.com/1999-4915/15/4/871
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Protests: are they French “police”?
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NATO Nazis
twitter.com/jeff_kaye/status/1644779924098777088
The NAZI officers in charge of NATO. Fact, not conspiracy theory!
🤨🤨🤨
Adolf Heusinger, Hitler’s Chief of Staff, went on to become Chairman of NATO Military Committee in 1961-1964.
Hans Speidel, NATO Commander of Central Europe (CCE) 1957-1963
Johann Steinhof, Chairman of the NATO Military Committee, 1971-1974
Johann von Kleimansegg – NATO CCE, 1967-1968
Ernst Ferber – NATO CCE, 1973-1975
Carl Schnel – NATO CCE, 1975-1977.
Franz Josef Schulze – NATO CCE, 1977-1979.
Ferdinand von Senger und Etterlin – NATO CCE, 1979-1983.
Shocking‼️
The update is part of a continuous process of reviewing such materials, working with guideline development groups composed of independent, international experts.
— Read on www.who.int/news/item/13-01-2023-who-updates-covid-19-guidelines-on-masks–treatments-and-patient-care
National infection prevention and control manual (NIPCM) for England
— Read on www.england.nhs.uk/national-infection-prevention-and-control-manual-nipcm-for-england/
Routine Covid-19 testing has now ended for most nurses and patients in England, the government has announced.
— Read on www.nursingtimes.net/news/coronavirus/government-ends-routine-covid-19-testing-across-health-and-social-care-03-04-2023/
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Protests: France
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Israel, Lebanon; attacks
Human genetic and immunological determinants of critical COVID-19 pneumonia
— Read on www.nature.com/articles/s41586-022-04447-0
Innate immune evasion strategies of SARS-CoV-2
— Read on www.nature.com/articles/s41579-022-00839-1
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Inquests and inquiries law blog
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Coronavirus: Bergamo, Italy
The UK has paused its infection survey, data that was important to those at highest risk
— Read on www.independent.co.uk/voices/covid-uk-cases-data-vulnerable-b2308825.html
Following COVID-19 infection, all subtypes of dementia, irrespective of a person’s previous dementia type, behave like rapidly progressive dementia.
— Read on neurosciencenews.com/covid-19-dementia-22938/
Infected Immune Cells In Brain Could Be Causing Long COVID Symptoms
— Read on www.medicaldaily.com/infected-immune-cells-brain-could-causing-long-covid-symptoms-469255
Company fined £80k after father-of-four loses lower arm | HSE Media Centre
— Read on press.hse.gov.uk/2023/03/22/company-fined-80k-after-father-of-four-loses-lower-arm/
Daniel Hartshorn suffered severe crush injuries and had to have his arm amputated at the elbow
— Read on www.liverpoolecho.co.uk/news/liverpool-news/dad-thought-going-die-after-26629024
While carrying out repairs, Daniel Hartshorn, an employee of Joloda Convery Services Ltd, was pulled into the machine.
— Read on www.lancs.live/news/lancashire-news/preston-dad-left-constant-pain-26630717
No5 Barristers Chambers – Interest on Special Damages | No5 Barristers’ Chambers
— Read on www.no5.com/media/publications/interest-on-special-damages/
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Politician watch: Lisa Nandy
Office-holders should ensure they are not described by their judicial role when taking part in media interviews.
— Read on www.lawgazette.co.uk/news/magistrate-warned-over-politically-sensitive-radio-interview/5115633.article
Court turns down request to extend one-year limitation period applicable to libel claims.
— Read on www.lawgazette.co.uk/law/you-should-have-read-the-cpr-judge-tells-litigant-in-person-/5115623.article
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Fire fighters: cancer risk
Israeli snipers shot Alaa al-Daly during Gaza’s Great March of Return. Prevented from becoming a champion on two legs, he vowed to do it with one
— Read on www.middleeasteye.net/opinion/gaza-hero-shot-Israel-denied-chance-compete-didnt-give-up
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Asbestos: The Asbestos Blog
Breach of duty in birth injury claims
— Read on www.12kbw.co.uk/webinar/birth-injuries-clinical-negligence-mini-series/
XBB.1.16 Omicron
— Read on www.cidrap.umn.edu/covid-19/who-tracking-omicron-xbb116-subvariant-rising-cases-some-countries
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Mick Wallace re: World Bank and IMF
Persistent SARS-CoV-2 infection in patients seemingly recovered from COVID-19
— Read on pathsocjournals.onlinelibrary.wiley.com/doi/10.1002/path.6035
Persistent Circulating Severe Acute Respiratory Syndrome Coronavirus 2 Spike Is Associated With Post-acute Coronavirus Disease 2019 Sequelae
— Read on academic.oup.com/cid/article/76/3/e487/6686531
Dexter Dias KC, sitting as a deputy High Court judge in PXC v AB College & Ors, stressed the importance of promptness and said that the local authority had to justify setting the default judgment aside.
— Read on www.lawgazette.co.uk/news/council-allowed-to-defend-6m-claim-despite-inexcusable-delay/5115587.article
Prisoners Bill rises from the ashes
— Read on rozenberg.substack.com/p/last-rites-for-the-bill-of-rights
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Cuba: USA blockade
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Stress: S&G; images case: Cahill
Praful Nargund
— Read on skwawkbox.org/2023/03/29/private-health-ceo-lined-up-to-try-to-take-corbyns-seat-for-starmer/
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Defamation: pre-action protocol
Resources | Letter before action in a complaint about untrue statements
— Read on www.farill.io/resources/templates/letter-before-action-in-a-complaint-about-untrue-statements
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Coronavirus: SARS-CoV-2 evolution
Stop the War Extends its Full Solidarity and Support to Jeremy Corbyn
Stop the War extends its full solidarity…
— Read on www.stopwar.org.uk/article/stop-the-war-coalition-statement-in-support-of-jeremy-corbyn/
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Clean air in schools
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S&G: stress claim: John Cahill
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Apartheid Israel
It is thought 20,000 children have been left with disabilities caused by sodium valproate.
— Read on www.bbc.co.uk/news/uk-england-london-42717083
Vaccine is one of the most effective strategies for preventing and controlling infectious diseases and some noninfectious diseases, especially cancers. Adjuvants and carriers have been appropriately added to the vaccine formulation to improve the immunogenicity of the antigen and induce long-lasting …
— Read on pubmed.ncbi.nlm.nih.gov/32531395/
Graphene oxide nanoparticles (GONPs) have attracted a lot of attention due to their many applications. These applications include batteries, super capacitors, drug delivery and biosensing. However, few studies have investigated the effects of these nanoparticles on the immune system. In this study, …
— Read on pubmed.ncbi.nlm.nih.gov/29495255/
Graphene oxide is not used in any COVID-19 vaccines
— Read on www.rmit.edu.au/news/factlab-meta/another-covid-myth-busted
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Cab rank rule
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HAVS: Finch Consulting
Office for National Statistics analysts estimate almost 1.7m Brits were carrying the virus on any given day in the week to March 13. This a jump of almost 14 per cent on the week before.
— Read on www.dailymail.co.uk/health/article-11898503/Covid-cases-jump-13-week-officials-warn-one-SEVENTEEN-people-infected.html
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NATO: Yugoslavia;
Share your videos with friends, family, and the world
— Read on m.youtube.com/watch
Genetic Technology (Precision Breeding) Act 2023
— Read on www.legislation.gov.uk/ukpga/2023/6/enacted
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USA attack Iranian forces in Syria
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Starmer Thatcher
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Lockheed Martin
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Capacity: fluctuating capacity
Nirmatrelvir tied to 26% lower risk of long COVID, 47% lower risk of death
— Read on www.cidrap.umn.edu/covid-19/nirmatrelvir-tied-26-lower-risk-long-covid-47-lower-risk-death
